Specialized Chemistry
Our proficient team boasts extensive expertise in delivering a diverse array of chemistry services, spanning from hydrophobic to hydrophilic compounds, with or without chromophores.
Our comprehensive offerings encompass:
- Synthesis of Lipid/Sphingolipids:
- De novo synthesis or manipulation of functional groups to produce lipid/sphingolipids.
- Synthesis of Nucleoside Bases and Nucleotides:
- Elaboration of nucleoside bases to nucleosides via glycosylation, followed by further transformation into nucleotides (mono-phosphates, tri-phosphates, etc.).
- Synthesis of Carbohydrates:
- Production of imino sugar, glycosyl acceptors/donors, oligosaccharides (tri and tetra), and functional group transformations on carbohydrates.
- Functional Group Transformations on Steroidal Skeletons:
- Modifications and manipulations of functional groups on steroidal structures.
- Synthesis of Novel Peptides:
- Utilizing both solution phase and solid phase approaches to synthesize innovative peptides.
- Multistep Stereo-selective Synthesis:
- Specific synthesis of natural products (Macroketone/Macrolides and Alkaloids) and their analogues featuring multiple asymmetric centers.
- Site-specific Labelling of Compounds:
- Incorporation of cold labels (D, 13C, and 15N) into compounds through site-specific labelling.
- Bioconjugation:
- Conjugation of small molecules with biotin or other fluorescent probes.
- PEGylation:
- Modification of biologically active small molecules through covalent linkage with polyethylene glycol units.
- Synthesis of Metabolites:
- Production of metabolites for research and analytical purposes.
- Synthesis of Organometallic Reagents:
- Preparation of organometallic reagents, including catalysts and precatalysts, utilizing Rhodium (Rh) and Palladium (Pd) metals.
- Photochemical Reactions:
- Synthesis of compounds through photochemical reactions using conventional UV or Blue LED light sources.